Publications – University of Copenhagen

CCG > Publications

Publications 2018

  1. Narimatsu H, Kaji H, Vakhrushev SY, Clausen H, Zhang H, Noro E, Togayachi A, Nagai-Okatani C, Kuno A, Zou X, Cheng L, Tao SC, Sun Y (2018): Current technologies for complex glycoproteomics and their applications to biology/disease-driven glycoproteomics. J Proteome Res. DOI: 10.1021/acs.jproteome.8b00515 [Epub ahead of print] 

  2. Hintze J, Ye Z, Narimatsu Y, Madsen TD, Joshi H, Linstedt A, Bachert C, Mandel U, Bennett EP, Vakhrushev SY, Schjoldager KT (2018): Probing the contribution of individual polypeptide GalNAc-transferase isoforms to the O-glycoproteome by inducible expression in isogenic cell lines. J Biol Chem DOI: 10.1074/jbc.RA118.004516 [Epub ahead of print] 

  3. de las Rivas M, Daniel EJP, Coelho H, Lira-Navarrete E, Raich L, Compañón I, Diniz A, Lagartera L, Jiménez-Barbero, Clausen H, Rovira C, Marcelo F, Corzana F, Gerken TA, Hurtado-Guerrero R. (2018): Structural and Mechanistic Insights into the Catalytic-Domain-Mediated Short-Range Glycosylation Preferences of GalNAc-T4. ACS Cent Sci. 4:1274-1290. DOI: 10.1021/acscentsci.8b00488

  4. Nygaard MB, Herlihy AM, Jeanneau C, Nielsen JE, Bennett EP, Jørgensen N, Clausen H, Mandel U, Meyts ER & Almstrup K (2018): Expression of the O-Glycosylation Enzyme GalNAc-T3 in the Equatorial Segment Correlates with the Quality of Spermatozoa. Int J Mol Sci 19, 2949. DOI:10.3390/ijms19102949

  5. Caval T, Zhu J, Tian W, Remmelzwaal SN, Yang Z, Clausen H, Heck AJR (2018): Targeted analysis of lysosomal directed proteins and their sites of mannose-6-phosphate modification. Mol Cell Proteomics Sep 20. DOI: 10.1074/mcp.RA118.000967
  6. Roed NK, Viola CM, Kristensen O, Schluckebier G, Norman M, Sajid W, Wade JD, Andersen AS, Kristensen C, Ganderton TR, Turkenburg JP, Meyts PD, Brzozowski AM (2018): Structures of insect Imp-L2 suggest an alternative strategy for regulating the bioavailability for insulin-like hormones. Nat Commun 9:3860. DOI: 10.1038/s41467-018-06192-3

  7. Caval T, Tian W, Yang Z, Clausen H & Heck AJ (2018): Direct quality control of glycoengineered erythropoietin variants. Nat Commun 9: 3342. DOI: 10.1038/s41467-018-05536-3

  8. Chen Y-H, Narimatsu Y, Clausen TM, Gomes C, Karlsson R, Steentoft C, Spliid CB, Gustavsson T, Salanti A, Persson A, Malmström A, Willén W, Ellervik U, Bennett EP, Mao Y, Clausen H & Yang Z (2018): The GAGOme: a cell-based library of displayed glycosaminoglycans. Nat methods (Epub ahead of print). DOI: 10.1038/s41592-018-0086-z

  9. Mathiesen CBK, Carlsson MC, Brand S, Möller SR, Idorn M, Straten PT, Pedersen AE, Dabelsteen S, Halim A, Würtzen PA, Brimnes J, Ipsen H, Petersen BL, Wandall HH. (2018). Genetically engineered cell factories produce glycoengineered vaccines that target antigen presenting cells and reduce antigen specific T-cell reactivity. J Allergy Clin Immunol Aug 17. DOI: 10.1016/j.jaci.2018.07.030

  10. Lamriben L, Oster ME, Tamura T, Tian W, Yang Z, Clausen H, Hebert DN (2018): EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity. J Biol Chem July (Epub ahead of print). DOI:10.1074/jbc.RA118.004183

  11. Coelho R, Marcos-Silva L, Mendes N, Pereira D, Brito C, Jacob F, Steentoft C, Mandel U, Clausen H, David L, Ricardo S. (2018 ): Mucins and Truncated O-Glycans Unveil Phenotypic Discrepancies between Serous Ovarian Cancer Cell Lines and Primary Tumours. Int J Mol Sci 19. DOI: 10.3390/ijms19072045

  12. Davidsen J, Larsen S, Coskun M, Gögenur I, Dahlgaard K, Bennett EP, Troelsen JT (2018): The VTI1A-TCF4 colon cancer fusion protein is a dominant negative regulator of Wnt signaling and is transcriptionally regulated by intestinal homeodomain factor CDX2. PLoS One Jul 5;13(7):e0200215. DOI: 10.1371/journal.pone.0200215

  13. King SL, Goth CK, Eckhard U, Joshi HJ, Haue AD, Vakhrushev S, Schjoldager K, Overall CM, Wandall HH (2018): TAILS N-Terminomics and proteomics reveal complex regulation of proteolytic cleavage by O-glycosylation. J Biol Chem. May 18;293(20):7629-7644. DOI: 10.1074/jbc.RA118.001978

  14. De Las Rivas M, Coelho H, Diniz A, Lira-Navarrete E, Compañón I, Jiménez-Barbero J, T Schjoldager K, P Bennett E, Y Vakhrushev S, Clausen H, Corzana F, Marcelo F, Hurtado-Guerrero R (2018): Structural analysis of a GalNAc-T2 mutant reveals an induced-fit catalytic mechanism for GalNAc-Ts. Chemistry Jun 12;24(33):8382-8392. DOI:10.1002/chem.201800701

  15. Schulz MA, Tian W, Mao Y, van Coillie  J, Sun L, Larsen JS, Chen YH, Kristensen C, Vakhrushev SY, Clausen H, Yang Z. (2018). Glycoengineering design options for IgG1 in CHO cells using precise gene editing. Glycobiology Jul 1;28(7):542-549.
    DOI: 10.1093/glycob/cwy022

  16. Bagdonaite I, Wandall HH (2018): Global Aspects of Viral Glycosylation. Glycobiology Jul 1;28(7):443-467. DOI: 10.1093/glycob/cwy021

  17. Wang S, Mao Y, Narimatsu Y, Ye Z, Tian W, Goth CK, Lira-Navarrete E, Pedersen NB, Benito-Vicente A, Martin C, Uribe KB, Hurtado-Guerrero R, Christoffersen C, Seidah NG, Nielsen R, Christensen EI, Hansen L, Bennett EP, Vakhrushev SY, Schjoldager KT, Clausen H. 2018. Site-specific O-glycosylation of members of the low-density lipoprotein receptor superfamily enhances ligand interactions. J Biol Chem May 11;293(19):7408-7422. DOI: 10.1074/jbc.M117.817981 

  18. Joshi HJ, Hansen L, Narimatsu Y, Freeze HH, Henrissat B, Bennett EP, Wandall HH, Clausen H, Schjoldager KT. (2018): Glycosyltransferase Genes That Cause Monogenic Congenital Disorders of Glycosylation Are Distinct From Glycosyltransferase Genes Associated with Complex Diseases. Glycobiology, May 1;28(5):284-294. DOI: 10.1093/glycob/cwy015

  19. Narimatsu Y, Joshi HJ, Zhang Y, Gomes C, Chen YH, Lorenzetti F, Furukawa S, Schjoldager K, Hansen L, Clausen H, Bennett EP, Wandall HH (2018): A validated gRNA library for CRISPR/Cas9 targeting of the human glycosyltransferase genome. Glycobiology May 1;28(5):295-305. DOI: 10.1093/glycob/cwx101

  20. Goth CK, Vakhrushev SY, Joshi HJ, Clausen H, Schjoldager KT. 2018. Fine-Tuning Limited Proteolysis: A Major Role for Regulated Site-Specific O-Glycosylation. Trends Biochem Sci April; 43(4):269-284. DOI: 10.1016/j.tibs.2018.02.005 

  21. Joshi HJ, Narimatsu Y, Schjoldager KT-G, Tytgat HLP, Aebi M, Clausen H, Halim A. (2018). SnapShot: O-Glycosylation Pathways across Kingdoms. Cell 172:632–632. DOI: 10.1016/j.cell.2018.01.016.

  22. Steentoft C, Migliorini D, King TR, Mandel U, June CH,  Posey AD. (2018): Glycan-Directed CAR-T Cells. Glycobiology Jan 23 (Epub ahead of print) DOI: 10.1093/glycob/cwy008