Banner Image Credit: Nature Reviews Molecular Cell Biology
Banner Image Credit: Nature Reviews Molecular Cell Biology




figure - informatics

The CCG hosts informatics resources to explore the vast amounts of data produced through our glycoengineering efforts. 












Büll, Christian, Hiren Jitendra Joshi, Henrik Clausen, and Yoshiki Narimatsu. 2020. “Cell-Based Glycan Arrays—A Practical Guide to Dissect the Human Glycome.” STAR Protocols 1 (1): 100017.

Chen, Yen-Hsi, Yoshiki Narimatsu, Thomas M Clausen, Catarina Gomes, Richard Karlsson, Catharina Steentoft, Charlotte B Spliid, et al. 2018. “The GAGOme: A Cell-Based Library of Displayed Glycosaminoglycans.” Nature Methods 15 (11): 881–88.

Joshi, Hiren J., Anja Jørgensen, Katrine T. Schjoldager, Adnan Halim, Leo A. Dworkin, Catharina Steentoft, Hans H. Wandall, Henrik Clausen, and Sergey Y. Vakhrushev. 2018. “GlycoDomainViewer: A Bioinformatics Tool for Contextual Exploration of Glycoproteomes.” Glycobiology 28 (3): 131–36.

Narimatsu, Yoshiki, Hiren J. Joshi, Zhang Yang, Catarina Gomes, Yen Hsi Chen, Flaminia C. Lorenzetti, Sanae Furukawa, et al. 2018. “A Validated GRNA Library for CRISPR/Cas9 Targeting of the Human Glycosyltransferase Genome.” Glycobiology 28 (5): 295–305.

Narimatsu, Yoshiki, Hiren J Joshi, Rebecca Nason, Julie Van Coillie, Richard Karlsson, Lingbo Sun, Zilu Ye, et al. 2019. “An Atlas of Human Glycosylation Pathways Enables Display of the Human Glycome by Gene Engineered Cells.” Molecular Cell 75 (2): 394-407.e5.

Schjoldager, K.T., Y. Narimatsu, H.J. Joshi, and H. Clausen. 2020. “Global View of Human Protein Glycosylation Pathways and Functions.” Nature Reviews Molecular Cell Biology.

Schulz, Morten A, Weihua Tian, Yang Mao, Julie Van Coillie, Lingbo Sun, Joachim S Larsen, Yen-Hsi Chen, et al. 2018. “Glycoengineering Design Options for IgG1 in CHO Cells Using Precise Gene Editing.” Glycobiology 28 (7): 542–49.

Steentoft, C., M. Fuhrmann, F. Battisti, J. Van Coillie, T.D. Madsen, D. Campos, A. Halim, et al. 2019. “A Strategy for Generating Cancer-Specific Monoclonal Antibodies to Aberrant O-Glycoproteins: Identification of a Novel Dysadherin-Tn Antibody.” Glycobiology 29 (4).

Steentoft, Catharina, Sergey Y Vakhrushev, Hiren J Joshi, Yun Kong, Malene B Vester-Christensen, Katrine T-B G Schjoldager, Kirstine Lavrsen, et al. 2013. “Precision Mapping of the Human O-GalNAc Glycoproteome through SimpleCell Technology.” The EMBO Journal 32 (10): 1478–88.

Tian, Weihua, Zilu Ye, Shengjun Wang, Morten Alder Schulz, Julie Van Coillie, Lingbo Sun, Yen-Hsi Chen, et al. 2019. “The Glycosylation Design Space for Recombinant Lysosomal Replacement Enzymes Produced in CHO Cells.” Nature Communications 10 (1): 1785.

Turnbull, Jeremy E. 2018. “Enhancing the Glycosciences Toolkit: New GAGs in the Lineup.” Nature Methods 15 (11): 867–68.

Yang, Zhang, Shengjun Wang, Adnan Halim, Morten Alder Schulz, Morten Frodin, Shamim H Rahman, Malene B Vester-Christensen, et al. 2015. “Engineered CHO Cells for Production of Diverse, Homogeneous Glycoproteins.” Nature Biotechnology 33 (8): 842–44.